Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 6/20 | 0.74 |
| ▸ | TAS2R46 | P59540 | 4/20 | 0.74 |
| ▸ | MEN1 | O00255 | 2/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.74 |
| ▸ | RECQL | P46063 | 1/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.74 |
| ▸ | TERT | O14746 | 1/20 | 0.74 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | STAT6 | P42226 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30444013 | 0.88 | PKM (0.56) | PKMTAS2R46MEN1KMT2ARECQL | |
| Costunolide SCHEMBL4086794 | 0.88 | TAS2R46 (0.88) | PKMTAS2R46MEN1KMT2ARECQL | |
| SCHEMBL17754224 | 0.85 | TAS2R46 (1.00) | PKMTAS2R46MEN1KMT2ARECQL | |
| Costunolide SCHEMBL30074732 | 0.85 | TAS2R46 (1.00) | PKMTAS2R46MEN1KMT2ARECQL | |
| Costunolide SCHEMBL14231146 | 0.85 | TAS2R46 (1.00) | PKMTAS2R46MEN1KMT2ARECQL | |
| Costunolide SCHEMBL92714 | 0.85 | TAS2R46 (1.00) | PKMTAS2R46MEN1KMT2ARECQL | |
| Costunolide SCHEMBL16369044 | 0.85 | TAS2R46 (1.00) | PKMTAS2R46MEN1KMT2ARECQL | |
| Costunolide SCHEMBL17005796 | 0.85 | TAS2R46 (1.00) | PKMTAS2R46MEN1KMT2ARECQL | |
| SCHEMBL4090929 | 0.85 | PKM (0.64) | PKMTAS2R46MEN1KMT2ARECQL | |
| SCHEMBL4090925 | 0.85 | PKM (0.64) | PKMTAS2R46MEN1KMT2ARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116396303-B | Gimalane-guaiane sesquiterpene dimer and preparation method and application thereof | 中国科学院昆明植物研究所 | 2025-02-18 | — | — | CN | disclosed |