SCHEMBL31487253

SCHEMBL31487253

O=C(NC1CC2COCC(C1)N2)c1c2n(c3ccccc13)CCCOC2

nearest known ligand 0.49

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR3A P46098 14/20 0.49
HTR4 Q13639 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31486805 0.92 HTR4 (0.44) HTR3AHTR4
SCHEMBL31486954 0.90 HTR3A (0.51) HTR3AHTR4
SCHEMBL31486795 0.90 HTR3A (0.51) HTR3AHTR4
SCHEMBL31486993 0.88 HTR3A (0.49) HTR3AHTR4
SCHEMBL31487350 0.86 HTR3A (0.49) HTR3AHTR4
Formic Acid SCHEMBL31487003 0.85 HTR3A (0.47) HTR3AHTR4
Trifluoroacetic Acid SCHEMBL31486790 0.83 HTR3A (0.52) HTR3A
SCHEMBL31486977 0.80 HTR4 (0.40) HTR3AHTR4
SCHEMBL31487099 0.79 HTR4 (0.47) HTR3AHTR4
SCHEMBL31486982 0.74 HTR2A (0.42) HTR3AHTR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025077825-A1 METHODS AND COMPOSITIONS FOR TREATING CARDIO-PULMONARY DISORDERS FAUNA BIO INCORPORATED (US) 2025-04-17 WO disclosed