SCHEMBL31487343

SCHEMBL31487343

CC(C)(C)OC(=O)N1C2COCC1CC(NC(=O)c1c3n(c4ccccc14)CCCCC3)C2

nearest known ligand 0.51

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR3A P46098 16/20 0.39
HTR4 Q13639 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31487122 0.96 HTR3A (0.40) HTR3AHTR4
SCHEMBL31486916 0.96 HTR3A (0.40) HTR3AHTR4
SCHEMBL31486899 0.90 HTR3A (0.39) HTR3AHTR4
SCHEMBL31486977 0.90 HTR4 (0.40) HTR3AHTR4
SCHEMBL31486995 0.89 HTR3A (0.43) HTR3AHTR4
SCHEMBL31486778 0.89 HTR3A (0.43) HTR3AHTR4
SCHEMBL31487185 0.88 HTR3A (0.42) HTR3A
SCHEMBL31486644 0.85 HTR3A (0.52) HTR3A
SCHEMBL31486858 0.84 HTR4 (0.41) HTR3AHTR4
SCHEMBL31486993 0.80 HTR3A (0.49) HTR3AHTR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025077825-A1 METHODS AND COMPOSITIONS FOR TREATING CARDIO-PULMONARY DISORDERS FAUNA BIO INCORPORATED (US) 2025-04-17 WO disclosed