SCHEMBL31488294

SCHEMBL31488294

C[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)OC(C)(C)C)C(=O)OC(C)(C)C

nearest known ligand 0.52

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ PTPN1 P18031 6/20 0.43
▸ MDM4 O15151 1/20 0.43
▸ TP53 P04637 1/20 0.43
▸ MDM2 Q00987 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30054532 0.93 MDM2 (0.49) PTPN1MDM4TP53MDM2
SCHEMBL27728772 0.91 MDM4 (0.49) MDM4TP53MDM2
SCHEMBL22492203 0.89 PTPN1 (0.47) PTPN1MDM4TP53MDM2
SCHEMBL22492204 0.89 PTPN1 (0.47) PTPN1MDM4TP53MDM2
SCHEMBL14729329 0.89 PTPN1 (0.47) PTPN1MDM4TP53MDM2
SCHEMBL18145431 0.89 PTPN1 (0.47) PTPN1MDM4TP53MDM2
SCHEMBL31094895 0.88 PTPN1 (0.47) PTPN1MDM2
SCHEMBL23446219 0.88 PTPN1 (0.47) PTPN1MDM4TP53MDM2
SCHEMBL31488424 0.88 FDFT1 (0.43) MDM4TP53MDM2
SCHEMBL29978024 0.87 PTPN1 (0.54) PTPN1MDM4TP53MDM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250296954-A1 METHOD FOR PRODUCING POLYPEPTIDE COMPOUND CHUBU UNIVERSITY EDUCATIONAL FOUNDATION (JP) 2025-09-25 — — US disclosed
EP-4516799-A1 METHOD FOR PRODUCING POLYPEPTIDE COMPOUND Chubu University Educational Foundation (JP) 2025-03-05 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250296954-A1 METHOD FOR PRODUCING POLYPEPTIDE COMPOUND VIP, NPR1, NPPA PTPN1 3407/4885MDM4 3947/4885TP53 2349/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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