Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | NAMPT | P43490 | 6/20 | 0.48 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | MET | P08581 | 1/20 | 0.48 |
| ▸ | PIM1 | P11309 | 1/20 | 0.48 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.48 |
| ▸ | LTK | P29376 | 1/20 | 0.48 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.48 |
| ▸ | CDK8 | P49336 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.48 |
| ▸ | CDK9 | P50750 | 1/20 | 0.48 |
| ▸ | NEK2 | P51955 | 1/20 | 0.48 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.48 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.48 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31489085 | 0.83 | TAS1R3 (0.46) | RAB9ANAMPTTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL31488876 | 0.80 | MEN1 (0.53) | MEN1KMT2ARAB9AGAANAMPT | |
| SCHEMBL31489000 | 0.79 | NAMPT (0.51) | NAMPTTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL3710550 | 0.79 | MEN1 (0.82) | MEN1KMT2ARAB9AGAANAMPT | |
| SCHEMBL31488795 | 0.77 | NAMPT (0.67) | NAMPT | |
| Hydrochloric Acid SCHEMBL31488963 | 0.76 | NAMPT (0.66) | NAMPT | |
| SCHEMBL31489143 | 0.76 | NAMPT (0.42) | NAMPTTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL31488821 | 0.76 | NAMPT (0.52) | RAB9ANAMPTNPC1MAPT | |
| SCHEMBL31488803 | 0.75 | NAMPT (0.69) | RAB9ANAMPTNPC1MAPTSMN1; SMN2 | |
| SCHEMBL28813844 | 0.74 | GAA (0.85) | MEN1KMT2ARAB9AGAANAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072437-A1 | HETEROARYL COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS | ALPHINA THERAPEUTICS, INC. (US) | 2025-04-03 | — | — | WO | disclosed |