Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 19/20 | 0.46 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31488927 | 0.83 | NAMPT (0.68) | NAMPT | |
| SCHEMBL31489030 | 0.83 | MAPK1 (0.36) | NAMPT | |
| SCHEMBL31488874 | 0.82 | NAMPT (0.64) | NAMPTCYP3A4CYP2C9 | |
| SCHEMBL31489170 | 0.82 | NAMPT (0.51) | NAMPT | |
| SCHEMBL31488810 | 0.78 | NAMPT (0.68) | NAMPT | |
| SCHEMBL31489001 | 0.74 | NAMPT (0.52) | NAMPTCYP3A4CYP2C9 | |
| SCHEMBL31488890 | 0.70 | NAMPT (0.69) | NAMPT | |
| SCHEMBL31488812 | 0.69 | TAS1R3 (0.51) | NAMPTCYP3A4CYP2C9 | |
| SCHEMBL31488983 | 0.68 | NAMPT (0.66) | NAMPTCYP3A4CYP2C9 | |
| SCHEMBL31488914 | 0.68 | RAB9A (0.41) | NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072437-A1 | HETEROARYL COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS | ALPHINA THERAPEUTICS, INC. (US) | 2025-04-03 | — | — | WO | disclosed |