SCHEMBL31489136

SCHEMBL31489136

C=CC(=O)NOS(=O)(=O)C(=O)S(=O)(=O)ONC(=O)C=C

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.36
ALDH1A1 P00352 2/20 0.36
MAPK1 P28482 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
FGFR4 P22455 1/20 0.32
TGM2 P21980 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27564886 0.78 TSHR (0.35) TSHRALDH1A1MAPK1TDP1TGM2
SCHEMBL10715597 0.77 TSHR (0.36) TSHRALDH1A1MAPK1TDP1FGFR4
SCHEMBL4543606 0.77 TGM2 (0.39) TSHRALDH1A1MAPK1TDP1FGFR4
SCHEMBL128041 0.77 TSHR (0.34) TSHRALDH1A1MAPK1TDP1TGM2
SCHEMBL2213304 0.75 TSHR (0.33) TSHRALDH1A1MAPK1TDP1TGM2
SCHEMBL31350429 0.75 TGM2 (0.35) TSHRALDH1A1MAPK1TDP1TGM2
SCHEMBL18916919 0.75 TSHR (0.33) TSHRALDH1A1MAPK1TDP1TGM2
SCHEMBL31350428 0.75 TGM2 (0.35) TSHRALDH1A1MAPK1TDP1TGM2
SCHEMBL27902730 0.74 TSHR (0.35) TSHRALDH1A1MAPK1TDP1TGM2
SCHEMBL4673569 0.74 TSHR (0.38) TSHRALDH1A1MAPK1TDP1TGM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119463012-A PH responsive hydrogel and preparation method and application thereof 中山大学 2025-02-18 CN disclosed