SCHEMBL4673569

SCHEMBL4673569

C=CC(=O)NOS(=O)(=O)CC

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.38
ALDH1A1 P00352 2/20 0.38
MAPK1 P28482 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
ZDHHC20 Q5W0Z9 1/20 0.37
ZDHHC2 Q9UIJ5 1/20 0.37
TGM2 P21980 3/20 0.33
PSMB11 A5LHX3 1/20 0.32
PSMA7 O14818 1/20 0.32
PSMB1 P20618 1/20 0.32
PSMA1 P25786 1/20 0.32
PSMA2 P25787 1/20 0.32
PSMA3 P25788 1/20 0.32
PSMA4 P25789 1/20 0.32
PSMB8 P28062 1/20 0.32
PSMB9 P28065 1/20 0.32
PSMA5 P28066 1/20 0.32
PSMB4 P28070 1/20 0.32
PSMB6 P28072 1/20 0.32
PSMB5 P28074 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL635230 0.86 ZDHHC20 (0.38) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL3634858 0.85 ZDHHC20 (0.37) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL19459592 0.83 ZDHHC20 (0.43) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL27464383 0.82 ZDHHC20 (0.42) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL9264991 0.82 ZDHHC20 (0.46) TSHRZDHHC20ZDHHC2HPGD
SCHEMBL3812635 0.82 TSHR (0.37) TSHRALDH1A1MAPK1TDP1
SCHEMBL10714172 0.81 TSHR (0.35) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL1698197 0.81 TSHR (0.39) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL28555015 0.81 ZDHHC20 (0.45) TSHRZDHHC20ZDHHC2HPGD
SCHEMBL28866456 0.81 TSHR (0.36) TSHRALDH1A1MAPK1TDP1ZDHHC20

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102348747-B Binders for coatings, having high water vapor permeability BASF SE 2013-08-14 CN claimed
CN-102348747-A Binders for coatings, having high water vapor permeability BASF SE 2012-02-08 CN claimed
CN-1492753-A Oxidizing composition for treating keratin materials, based on at least one ethylenically unsaturated monomer containing sulphonic groups and an amphiphilic polymer comprising hydrophobic portions �ź㴫 2004-04-28 CN claimed
US-11492760-B2 Softener composition KEMIRA OYJ (FI) 2022-11-08 US disclosed
CN-109072565-B Softener compositions 凯米拉公司 2021-07-30 CN disclosed
CN-108130801-B Method for producing activated colloidal silica for use in papermaking 艺康美国股份有限公司 2020-11-24 CN disclosed
US-20200149223-A1 SOFTENER COMPOSITION KEMIRA OYJ (FI) 2020-05-14 US disclosed
EP-3423632-B1 A SOFTENER COMPOSITION KEMIRA OYJ (FI) 2020-05-13 EP disclosed
US-10570567-B2 Softener composition KEMIRA OYJ (FI) 2020-02-25 US disclosed
US-10458068-B2 Method for producing paper KEMIRA OYJ (FI) 2019-10-29 US disclosed
US-10435843-B2 Method for producing paper KEMIRA OYJ (FI) 2019-10-08 US disclosed
US-20010023752-A1 Method of increasing drainage in papermaking using colloidal borosilicates ECOLAB USA INC. 2001-09-27 US disclosed
US-20010023753-A1 Method for flocculating a papermaking furnish using colloidal borosilicates ECOLAB USA INC. 2001-09-27 US disclosed
CN-1303875-A Copolymer of cement admixture, its preparing method and use NIPPON CATALYTIC CHEM IND (JP) 2001-07-18 CN disclosed
WO-2000075074-A1 STABLE SILICA SOLS OF HIGH SURFACE AREA AND IMPROVED ACTIVITY NALCO CHEMICAL COMPANY (US) 2000-12-14 WO disclosed
EP-1023241-A1 COLLOIDAL BOROSILICATES AND THEIR USE IN THE PRODUCTION OF PAPER NALCO CHEMICAL COMPANY (US) 2000-08-02 EP disclosed
CN-1261599-A Cement additire, cement composition and polycarboxylic acid polymer NIPPON CATALYTIC CHEM IND (JP) 2000-08-02 CN disclosed
CN-1252394-A Cement additive NIPPON CATALYTIC CHEM IND (JP) 2000-05-10 CN disclosed
WO-1999016708-A1 COLLOIDAL BOROSILICATES AND THEIR USE IN THE PRODUCTION OF PAPER NALCO CHEMICAL COMPANY (US) 1999-04-08 WO disclosed
CN-1201766-A Cement admixture and cement composition NIPPON CATALYTIC CHEM IND (JP) 1998-12-16 CN disclosed