Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 1/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31489496 | 1.00 | LPL (0.33) | LPLLIPGJAK2JAK1TYK2 | |
| SCHEMBL31489593 | 0.87 | CREBBP (0.41) | LPLLIPGPDK2 | |
| SCHEMBL31489264 | 0.87 | CREBBP (0.41) | LPLLIPGPDK2 | |
| SCHEMBL31489237 | 0.83 | PDK2 (0.34) | LPLLIPGPDK2CXCR2 | |
| SCHEMBL31489863 | 0.83 | PDK2 (0.34) | LPLLIPGPDK2CXCR2 | |
| SCHEMBL31489590 | 0.79 | CYP17A1 (0.38) | JAK2JAK1TYK2JAK3CYP17A1 | |
| SCHEMBL31489746 | 0.79 | CYP17A1 (0.38) | JAK2JAK1TYK2JAK3CYP17A1 | |
| SCHEMBL22585809 | 0.79 | LPL (0.43) | LPLLIPGJAK2JAK1TYK2 | |
| SCHEMBL31489271 | 0.79 | LPL (0.43) | LPLLIPGJAK2JAK1TYK2 | |
| SCHEMBL31489712 | 0.79 | LPL (0.43) | LPLLIPGJAK2JAK1TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072395-A1 | TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-04-03 | — | — | WO | disclosed |