SCHEMBL31489237

SCHEMBL31489237

CC(F)(F)[C@@H](c1ccc(F)cc1)n1cc(-c2cccc(B3OC(C)(C)C(C)(C)O3)c2F)cn1

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 6/20 0.34
LPL P06858 1/20 0.33
LIPG Q9Y5X9 1/20 0.33
PDK4 Q16654 1/20 0.31
CXCR2 P25025 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31489863 1.00 PDK2 (0.34) PDK2LPLLIPGPDK4CXCR2
SCHEMBL31489264 0.86 CREBBP (0.41) PDK2LPLLIPG
SCHEMBL31489593 0.86 CREBBP (0.41) PDK2LPLLIPG
SCHEMBL31489197 0.83 LPL (0.33) PDK2LPLLIPGCXCR2
SCHEMBL31489496 0.83 LPL (0.33) PDK2LPLLIPGCXCR2
SCHEMBL31489182 0.79 PDK2 (0.36) PDK2PDK4
SCHEMBL31489229 0.79 PDK2 (0.36) PDK2PDK4
SCHEMBL31489328 0.79 FFAR1 (0.44) LPLLIPGCXCR2
SCHEMBL31489214 0.79 FFAR1 (0.44) LPLLIPGCXCR2
SCHEMBL22040321 0.76 PDK2 (0.42) PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025072395-A1 TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2025-04-03 WO disclosed