Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 10/20 | 0.34 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.31 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3148924 | 0.68 | NOTUM (0.34) | NOTUMMAP3K5KEAP1EGLN2 | |
| SCHEMBL27793766 | 0.60 | — | — | |
| SCHEMBL16323410 | 0.60 | CYP17A1 (0.40) | NOTUMCYP17A1 | |
| SCHEMBL17728484 | 0.59 | NOTUM (0.37) | NOTUMMAP3K5KEAP1CYP17A1 | |
| SCHEMBL10447781 | 0.58 | NOTUM (0.78) | NOTUMKEAP1 | |
| SCHEMBL2732141 | 0.57 | EGLN2 (0.39) | NOTUMKEAP1EGLN2 | |
| SCHEMBL28780246 | 0.56 | NOTUM (0.41) | NOTUMKEAP1 | |
| SCHEMBL6179485 | 0.56 | — | — | |
| SCHEMBL4281004 | 0.56 | — | — | |
| SCHEMBL18075990 | 0.56 | MAP3K5 (0.43) | NOTUMMAP3K5KEAP1EGLN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099776-B1 | CHELATING AGENT | UNIV MUENCHEN TECH (DE) | 2015-10-07 | — | — | EP | disclosed |
| US-20100081799-A1 | Chelating Agent | TECHNISCHE UNIVERSITAT MUNCHEN (DE) | 2010-04-01 | — | — | US | disclosed |
| EP-2099776-A1 | CHELATING AGENT | Technische Universität München (DE) | 2009-09-16 | — | — | EP | disclosed |
| WO-2008068516-A1 | CHELATING AGENT | Technische Universität München (DE) | 2008-06-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100081799-A1 | Chelating Agent | HRH3, C3AR1, H1-3 | NOTUM 3722/4885MAP3K5 4778/4885KEAP1 465/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.