Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.30 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.30 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.30 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.30 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.30 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31489375 | 0.91 | MKNK1 (0.31) | ROCK2MKNK1MAPK1 | |
| SCHEMBL31489315 | 0.90 | ROCK2 (0.32) | ROCK2PIK3CDPIK3CAPIK3CG | |
| SCHEMBL31489578 | 0.88 | ROCK2 (0.31) | ROCK2 | |
| SCHEMBL31489134 | 0.86 | MEN1 (0.34) | ROCK2MEN1GAAMAPTKMT2A | |
| SCHEMBL31489457 | 0.86 | MAPK1 (0.32) | ROCK2MKNK1PIK3CDPIK3CAPIK3CG | |
| SCHEMBL31489860 | 0.86 | PIK3CD (0.32) | ROCK2MKNK1PIK3CDPIK3CAPIK3CG | |
| SCHEMBL31489528 | 0.81 | CCNT1 (0.31) | ROCK2 | |
| SCHEMBL31489408 | 0.78 | CCNT1 (0.31) | ROCK2 | |
| SCHEMBL31489923 | 0.78 | ROCK2 (0.30) | ROCK2 | |
| SCHEMBL31489335 | 0.78 | PIK3CG (0.36) | MKNK1PIK3CDPIK3CAPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072395-A1 | TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-04-03 | — | — | WO | disclosed |