Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 9/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 2/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.35 |
| ▸ | CLK1 | P49759 | 3/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31489706 | 1.00 | CREBBP (0.43) | CREBBPRIPK1BRD4GPR55CLK1 | |
| SCHEMBL31489474 | 0.76 | CREBBP (0.46) | CREBBPGPR55CLK1DYRK1AJAK2 | |
| SCHEMBL31489417 | 0.76 | CREBBP (0.46) | CREBBPGPR55CLK1DYRK1AJAK2 | |
| SCHEMBL31489263 | 0.75 | CREBBP (0.46) | CREBBPBRD4GPR55CLK1DYRK1A | |
| SCHEMBL31489452 | 0.73 | CREBBP (0.45) | CREBBPGPR55CLK1DYRK1AJAK2 | |
| SCHEMBL31489790 | 0.73 | CREBBP (0.45) | CREBBPGPR55CLK1DYRK1AJAK2 | |
| SCHEMBL31489202 | 0.73 | CREBBP (0.46) | CREBBPBRD4GPR55 | |
| SCHEMBL31489519 | 0.73 | CREBBP (0.46) | CREBBPBRD4GPR55 | |
| SCHEMBL22777630 | 0.72 | CREBBP (0.51) | CREBBPBRD4 | |
| SCHEMBL31489687 | 0.70 | CREBBP (0.43) | CREBBPBRD4GPR55CLK1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072395-A1 | TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-04-03 | — | — | WO | disclosed |