Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 10/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 5/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | CLK1 | P49759 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31489664 | 1.00 | CREBBP (0.42) | CREBBPRIPK1NTRK1BRD4PIK3CG | |
| SCHEMBL31489633 | 0.89 | RIPK1 (0.40) | CREBBPRIPK1NTRK1BRD4PIK3CG | |
| SCHEMBL31489701 | 0.89 | RIPK1 (0.40) | CREBBPRIPK1NTRK1BRD4PIK3CG | |
| SCHEMBL31489733 | 0.87 | PIK3CG (0.34) | CREBBPRIPK1PIK3CG | |
| SCHEMBL31489586 | 0.83 | CREBBP (0.39) | CREBBPNTRK1BRD4PIK3CGJAK2 | |
| SCHEMBL31489221 | 0.82 | CREBBP (0.47) | CREBBPRIPK1BRD4PIK3CG | |
| SCHEMBL31489822 | 0.82 | CREBBP (0.38) | CREBBPRIPK1NTRK1PIK3CG | |
| SCHEMBL31489295 | 0.82 | CREBBP (0.38) | CREBBPRIPK1NTRK1PIK3CG | |
| SCHEMBL31489824 | 0.82 | CREBBP (0.47) | CREBBPRIPK1BRD4PIK3CG | |
| SCHEMBL31489312 | 0.81 | PIK3CG (0.41) | CREBBPRIPK1NTRK1PIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072395-A1 | TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-04-03 | — | — | WO | disclosed |