Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 11/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 10/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.32 |
| ▸ | PAK4 | O96013 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.32 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.32 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31489307 | 1.00 | PIK3CG (0.34) | PIK3CGPIK3CDHSP90AA1RIPK1PIK3CA | |
| SCHEMBL31489599 | 0.93 | PIK3CG (0.38) | PIK3CGPIK3CDHSP90AA1RIPK1PIK3CA | |
| SCHEMBL31489669 | 0.92 | PIK3CG (0.35) | PIK3CGPIK3CDHSP90AA1RIPK1PIK3CA | |
| SCHEMBL31489512 | 0.88 | RIPK1 (0.36) | PIK3CGPIK3CDRIPK1PIK3CAPAK4 | |
| SCHEMBL31489902 | 0.88 | PIK3CG (0.36) | PIK3CGPIK3CDHSP90AA1RIPK1PIK3CA | |
| SCHEMBL31489335 | 0.87 | PIK3CG (0.36) | PIK3CGPIK3CDHSP90AA1RIPK1PIK3CA | |
| SCHEMBL31489300 | 0.86 | PIK3CG (0.39) | PIK3CGPIK3CDRIPK1PIK3CAPAK4 | |
| SCHEMBL31489697 | 0.86 | PIK3CG (0.39) | PIK3CGPIK3CDRIPK1PIK3CAPAK4 | |
| SCHEMBL31489539 | 0.86 | PIK3CG (0.34) | PIK3CGPIK3CDRIPK1PIK3CAPAK4 | |
| SCHEMBL31489445 | 0.85 | PIK3CG (0.35) | PIK3CGPIK3CDHSP90AA1RIPK1PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072395-A1 | TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-04-03 | — | — | WO | disclosed |