⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31489757 | 0.79 | BACE1 (0.41) | — | |
| SCHEMBL31489427 | 0.78 | APP (0.32) | — | |
| SCHEMBL31489388 | 0.77 | AAK1 (0.32) | — | |
| SCHEMBL856765 | 0.74 | AHR (0.40) | — | |
| SCHEMBL30385381 | 0.73 | — | — | |
| SCHEMBL20472412 | 0.73 | AHR (0.41) | — | |
| SCHEMBL20472591 | 0.71 | PCSK9 (0.31) | — | |
| SCHEMBL31489361 | 0.71 | SSTR4 (0.31) | — | |
| SCHEMBL31507676 | 0.71 | TDP2 (0.32) | — | |
| SCHEMBL25439769 | 0.70 | CSNK2A1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072395-A1 | TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-04-03 | — | — | WO | disclosed |