SCHEMBL31489427

SCHEMBL31489427

CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)c1nc2cc(-c3nc(Cl)ccc3F)c(F)cn2n1

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31489552 0.84 TDP2 (0.34) APP
SCHEMBL31489388 0.82 AAK1 (0.32)
SCHEMBL31489352 0.78
SCHEMBL31489267 0.75
SCHEMBL31489293 0.74 TDP2 (0.33) APP
SCHEMBL31489812 0.72 TDP2 (0.34) APP
SCHEMBL31489757 0.71 BACE1 (0.41)
SCHEMBL31507676 0.71 TDP2 (0.32) APP
SCHEMBL31489548 0.70 TDP2 (0.35)
SCHEMBL856765 0.69 AHR (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025072395-A1 TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2025-04-03 WO disclosed