Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.45 |
| ▸ | RAB9A | P51151 | 7/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31489622 | 0.83 | KDM4E (0.39) | NPC1RAB9AKDM4EHCRTR1CASP3 | |
| SCHEMBL31489689 | 0.75 | AHR (0.50) | NPC1RAB9AKDM4EHCRTR1CASP3 | |
| SCHEMBL31489505 | 0.75 | KDM4E (0.37) | NPC1RAB9AKDM4EHCRTR1CASP3 | |
| SCHEMBL26857578 | 0.74 | PIK3CG (0.49) | NPC1RAB9AKDM4EHCRTR1CASP3 | |
| SCHEMBL20265119 | 0.73 | AHR (0.47) | NPC1RAB9AKDM4EHCRTR1CASP3 | |
| SCHEMBL31489520 | 0.73 | KDM4E (0.41) | KDM4E | |
| SCHEMBL31489565 | 0.71 | LPL (0.33) | NPC1RAB9AKDM4EMAPTMEN1 | |
| SCHEMBL31489209 | 0.70 | MAPT (0.32) | KDM4EMAPTMEN1KMT2A | |
| SCHEMBL31489531 | 0.68 | KDM4E (0.39) | KDM4E | |
| SCHEMBL18586369 | 0.66 | KDM4E (0.47) | NPC1RAB9AKDM4EMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072395-A1 | TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-04-03 | — | — | WO | disclosed |