SCHEMBL31489209

SCHEMBL31489209

Cc1ccc(C)n1-c1nc2cc(I)cc(F)n2n1

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31489454 0.73 LPL (0.35)
SCHEMBL31489505 0.72 KDM4E (0.37) MAPTMEN1KMT2AKDM4E
SCHEMBL31489241 0.70 PIK3CG (0.40) KDM4E
SCHEMBL31489419 0.70 NPC1 (0.45) MAPTMEN1KMT2AKDM4E
SCHEMBL31489137 0.69 KDM4E (0.30) KDM4E
SCHEMBL31489622 0.65 KDM4E (0.39) MAPTMEN1KMT2AKDM4E
SCHEMBL31489520 0.64 KDM4E (0.41) KDM4E
SCHEMBL31489696 0.63 KDM4E (0.37) MAPTKDM4E
SCHEMBL31489379 0.63 KDM4E (0.37) KDM4E
SCHEMBL13052936 0.61 KDM4E (0.52) MAPTMEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025072395-A1 TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2025-04-03 WO disclosed