Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 3/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.31 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.30 |
| ▸ | KCNK3 | O14649 | 4/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31489557 | 1.00 | CYP17A1 (0.37) | CYP17A1ADORA2AADORA1PSEN1PSEN2 | |
| SCHEMBL31489358 | 0.84 | CYP17A1 (0.39) | CYP17A1METKDM4EALDH1A1GAA | |
| SCHEMBL31489601 | 0.84 | CYP17A1 (0.39) | CYP17A1METKDM4EALDH1A1GAA | |
| SCHEMBL31489270 | 0.83 | CYP17A1 (0.38) | CYP17A1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL31489728 | 0.83 | CYP17A1 (0.38) | CYP17A1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL31489582 | 0.72 | ADORA2A (0.32) | CYP17A1ADORA2AADORA1 | |
| SCHEMBL31489591 | 0.71 | CREBBP (0.39) | CYP17A1METGPR55 | |
| SCHEMBL31489224 | 0.71 | CREBBP (0.39) | CYP17A1METGPR55 | |
| SCHEMBL32659828 | 0.70 | ADCY10 (0.30) | — | |
| SCHEMBL31489718 | 0.68 | CYP17A1 (0.45) | CYP17A1METKDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072395-A1 | TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-04-03 | — | — | WO | disclosed |