Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 7/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 4/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.31 |
| ▸ | TDP2 | O95551 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31489529 | 1.00 | CREBBP (0.38) | CREBBPRIPK1ROCK2BRD4JAK2 | |
| SCHEMBL31489497 | 0.93 | CREBBP (0.35) | CREBBPRIPK1ROCK2BRD4JAK2 | |
| SCHEMBL31489247 | 0.87 | CREBBP (0.38) | CREBBPBRD4JAK2 | |
| SCHEMBL31489700 | 0.83 | CREBBP (0.33) | CREBBPRIPK1ROCK2BRD4 | |
| SCHEMBL31489468 | 0.83 | CREBBP (0.33) | CREBBPRIPK1ROCK2BRD4 | |
| SCHEMBL31489543 | 0.83 | RIPK1 (0.33) | CREBBPRIPK1ROCK2 | |
| SCHEMBL31489789 | 0.83 | RIPK1 (0.33) | CREBBPRIPK1ROCK2 | |
| SCHEMBL31489310 | 0.83 | TDP2 (0.32) | RIPK1ROCK2JAK2TDP2 | |
| SCHEMBL31489211 | 0.80 | CREBBP (0.43) | CREBBPRIPK1ROCK2PIK3CAPIK3CG | |
| SCHEMBL31489964 | 0.80 | CREBBP (0.43) | CREBBPRIPK1ROCK2PIK3CAPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072395-A1 | TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-04-03 | — | — | WO | disclosed |