Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 5/20 | 0.32 |
| ▸ | TDP2 | O95551 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.30 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31489798 | 1.00 | ROCK2 (0.34) | ROCK2RIPK1TDP2MDM2CHEK1 | |
| SCHEMBL31489154 | 0.87 | KDM4E (0.31) | KDM4ENPC1ALDH1A1HPGDRAB9A | |
| SCHEMBL31489395 | 0.84 | NTRK1 (0.31) | RIPK1 | |
| SCHEMBL31489609 | 0.83 | CYP11B2 (0.31) | — | |
| SCHEMBL31489829 | 0.83 | CYP11B2 (0.31) | — | |
| SCHEMBL31489578 | 0.83 | ROCK2 (0.31) | ROCK2 | |
| SCHEMBL31489338 | 0.83 | — | — | |
| SCHEMBL31489710 | 0.83 | CCNT1 (0.31) | ROCK2 | |
| SCHEMBL31489528 | 0.83 | CCNT1 (0.31) | ROCK2 | |
| SCHEMBL31489923 | 0.83 | ROCK2 (0.30) | ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072395-A1 | TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-04-03 | — | — | WO | disclosed |