SCHEMBL31490367

SCHEMBL31490367

Nc1cc(Cl)c(F)c(C(=O)O)c1F

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.39
KEAP1 Q14145 2/20 0.38
CYP3A4 P08684 1/20 0.38
ALDH1A1 P00352 4/20 0.38
DPP4 P27487 1/20 0.38
POLB P06746 1/20 0.38
KMO O15229 1/20 0.35
TTR P02766 1/20 0.34
KDM4E B2RXH2 2/20 0.33
TSHR P16473 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
HSD17B10 Q99714 1/20 0.33
NFE2L2 Q16236 1/20 0.33
MAPK1 P28482 1/20 0.33
PYGL P06737 1/20 0.33
DAO P14920 3/20 0.32
TP53 P04637 1/20 0.32
CASP1 P29466 1/20 0.32
GFER P55789 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8377346 0.84 DPP4 (0.44) KEAP1ALDH1A1DPP4KMOTTR
SCHEMBL670666 0.81 CA1 (0.45) GAAKEAP1CYP3A4ALDH1A1POLB
SCHEMBL3577396 0.79 DPP4 (0.38) KEAP1CYP3A4ALDH1A1DPP4POLB
SCHEMBL20575325 0.78 DPP4 (0.50) KEAP1ALDH1A1DPP4POLBKMO
SCHEMBL3574434 0.75 DPP4 (0.47) KEAP1ALDH1A1DPP4POLBKMO
SCHEMBL1398113 0.73 KEAP1 (0.41) KEAP1CYP3A4ALDH1A1DPP4POLB
SCHEMBL31148735 0.73 GAA (0.35) GAAKEAP1CYP3A4ALDH1A1DPP4
SCHEMBL10344814 0.72 CYP3A4 (0.48) GAACYP3A4ALDH1A1DPP4POLB
SCHEMBL8762020 0.72 CYP3A4 (0.44) GAACYP3A4ALDH1A1DPP4POLB
SCHEMBL19130846 0.72 KEAP1 (0.39) GAAKEAP1CYP3A4ALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119486466-A Passivation layer, perovskite solar cell, preparation method of perovskite solar cell, laminated cell and photovoltaic module 天合光能股份有限公司 2025-02-18 CN disclosed