Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | APP | P05067 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | FOS | P01100 | 1/20 | 0.43 |
| ▸ | JUN | P05412 | 1/20 | 0.43 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.43 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31490430 | 0.86 | PTGS2 (0.56) | TRPM8NPC1L3MBTL1RAB9AKMT2A | |
| SCHEMBL28501196 | 0.84 | NPC1 (0.72) | TRPM8NPC1L3MBTL1RAB9AAPP | |
| SCHEMBL22187006 | 0.80 | TRPM8 (0.55) | TRPM8NPC1L3MBTL1RAB9AAPP | |
| SCHEMBL20777300 | 0.80 | TRPM8 (0.55) | TRPM8NPC1L3MBTL1RAB9AAPP | |
| SCHEMBL31490472 | 0.79 | TRPM8 (0.60) | TRPM8NPC1L3MBTL1RAB9AKMT2A | |
| SCHEMBL31490310 | 0.78 | TRPM8 (0.76) | TRPM8NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL22074363 | 0.77 | TRPM8 (0.53) | TRPM8NPC1L3MBTL1RAB9AAPP | |
| SCHEMBL20773115 | 0.77 | TRPM8 (0.53) | TRPM8NPC1L3MBTL1RAB9AAPP | |
| SCHEMBL29779971 | 0.77 | TRPM8 (0.53) | TRPM8NPC1L3MBTL1RAB9AAPP | |
| SCHEMBL22074377 | 0.74 | TRPM8 (0.55) | TRPM8NPC1L3MBTL1RAB9AAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119486725-A | (2E) Mixtures and uses of (E) -3- (1, 3-benzodioxol-5-yl) -N-phenyl-N- (tetrahydro-3-furanyl) -2-propenamide | 西姆莱斯有限公司 | 2025-02-18 | — | — | CN | disclosed |