SCHEMBL31490481

SCHEMBL31490481

CNC(=O)c1nc(N)c2ncn([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c2n1

nearest known ligand 0.71

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 6/20 0.69
ADORA3 P0DMS8 5/20 0.69
ADORA2B P29275 4/20 0.69
ADORA1 P30542 3/20 0.69
ADRA1A P35348 1/20 0.69
LMNA P02545 1/20 0.66
NT5E P21589 1/20 0.66
HIF1A Q16665 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28774024 0.83 ADORA2A (0.83) ADORA2AADORA3ADORA2BADORA1LMNA
Acetic Acid SCHEMBL4399000 0.82 ADORA3 (0.72) ADORA2AADORA3ADORA2BADORA1ADRA1A
SCHEMBL5794230 0.82 ADORA2A (0.67) ADORA2AADORA3ADORA2BADORA1LMNA
SCHEMBL2343062 0.82 ADORA2A (0.67) ADORA2AADORA3ADORA2BADORA1LMNA
SCHEMBL7897993 0.82 ADORA2A (0.67) ADORA2AADORA3ADORA2BADORA1LMNA
Regadenoson Anhydrous SCHEMBL29462353 0.82 ADORA2A (1.00) ADORA2AADORA3ADORA2BADORA1ADRA1A
Regadenoson Anhydrous SCHEMBL21710782 0.82 ADORA2A (1.00) ADORA2AADORA3ADORA2BADORA1ADRA1A
SCHEMBL10089232 0.82 ADORA2A (0.71) ADORA2AADORA3ADORA2BADORA1ADRA1A
Regadenoson Anhydrous SCHEMBL678893 0.82 ADORA2A (1.00) ADORA2AADORA3ADORA2BADORA1ADRA1A
SCHEMBL11516417 0.82 ADORA2A (0.77) ADORA2AADORA3ADORA2BADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122070366-A Cyclic RNA compositions and methods 欧纳医疗公司 2026-05-19 CN disclosed
CN-119866376-A Self-amplifying RNA encoding influenza virus antigen 辉瑞公司 2025-04-22 CN disclosed