Regadenoson Anhydrous

Regadenoson Anhydrous

SCHEMBL678893

CNC(=O)c1cnn(-c2nc(N)c3ncn([C@@H]4O[C@H](CO)[C@@H](O)[C@H]4O)c3n2)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADORA2A

The experimentally established mechanism targets of Regadenoson Anhydrous. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ADORA2A known ✓ P29274 14/20 1.00
ADORA3 P0DMS8 9/20 1.00
ADORA1 P30542 6/20 1.00
ADORA2B P29275 1/20 1.00
ADRA1A P35348 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Regadenoson Anhydrous SCHEMBL19387116 1.00 ADORA2A (1.00) ADORA2AADORA3ADORA1ADORA2BADRA1A
Regadenoson Anhydrous SCHEMBL20128455 1.00 ADORA2A (1.00) ADORA2AADORA3ADORA1ADORA2BADRA1A
Regadenoson Anhydrous SCHEMBL14131217 1.00 ADORA2A (1.00) ADORA2AADORA3ADORA1ADORA2BADRA1A
Regadenoson Anhydrous SCHEMBL12958830 1.00 ADORA2A (1.00) ADORA2AADORA3ADORA1ADORA2BADRA1A
Regadenoson Anhydrous SCHEMBL8925057 1.00 ADORA2A (1.00) ADORA2AADORA3ADORA1ADORA2BADRA1A
Regadenoson Anhydrous SCHEMBL278152 1.00 ADORA2A (1.00) ADORA2AADORA3ADORA1ADORA2BADRA1A
Regadenoson Anhydrous SCHEMBL13462149 1.00 ADORA2A (1.00) ADORA2AADORA3ADORA1ADORA2BADRA1A
Regadenoson Anhydrous SCHEMBL15472806 1.00 ADORA2A (1.00) ADORA2AADORA3ADORA1ADORA2BADRA1A
Regadenoson Anhydrous SCHEMBL6745611 1.00 ADORA2A (1.00) ADORA2AADORA3ADORA1ADORA2BADRA1A
Regadenoson Anhydrous SCHEMBL21710782 1.00 ADORA2A (1.00) ADORA2AADORA3ADORA1ADORA2BADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 220 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230301973-A1 TREATMENT OF DIFFUSE INTRINSIC PONTINE GLIOMA FLOHIL JACOB ARY (NL) 2023-09-28 US claimed
US-20230285556-A1 METHODS AND COMPOSITIONS FOR TREATING CANCER OMEROS CORPORATION 2023-09-14 US claimed
WO-2023039578-A1 METHODS AND COMPOSITIONS FOR TREATING CANCER OMEROS CORPORATION (US) 2023-03-16 WO claimed
EP-2789624-B1 Stable solid forms of regadenoson AMRI ITALY SRL (IT) 2020-09-23 EP claimed
WO-2018106118-A1 TREATMENT OF DIFFUSE INTRINSIC PONTINE GLIOMA FLOHIL JACOB ARY (NL) 2018-06-14 WO claimed
US-20170056381-A1 PYRIDOXAMINE FOR THE TREATMENT OF SICKLE CELL DISEASE, THALASSEMIA AND RELATED BLOOD DISEASES NANOMETICS LLC (US) 2017-03-02 US claimed
US-9441006-B2 Polymorph of 2-[4-[(methylamino)carbonyl]-1H-pyrazol-1-yl]adenosine FARMAK, A.S. (CZ) 2016-09-13 US claimed
WO-2014177119-A1 NEW POLYMORPH OF 2-[4-F(METHYLAMINO)CARBONYL]-1H-PYRAZOL-1-YL]ADENOSINE AND METHOD OF ITS PREPARATION FARMAK, A.S. (CZ) 2014-11-06 WO claimed
US-20140323712-A1 POLYMORPH OF 2-[4-[(METHYLAMINO)CARBONYL]-1H-PYRAZOL-1-YL]ADENOSINE FARMAK, A.S. (CZ) 2014-10-30 US claimed
US-6403567-B1 N-pyrazole A2A adenosine receptor agonists CV THERAPEUTICS, INC. 2002-06-11 US claimed
US-12551475-B2 Methods and compositions for treating RNA viral infections MODEL MEDICINES, INC. (US) 2026-02-17 US disclosed
EP-4667008-A2 METHODS AND COMPOSITIONS FOR TREATING RNA VIRAL INFECTIONS Model Medicines, Inc. (US) 2025-12-24 EP disclosed
CN-119185343-A Ruiganosheng in ultrasound application in cardiography 南京瑞克卫生物医药有限公司 2024-12-27 CN disclosed
US-20230285556-A1 METHODS AND COMPOSITIONS FOR TREATING CANCER OMEROS CORPORATION 2023-09-14 US disclosed
US-20230248712-A1 METHODS AND COMPOSITIONS FOR TREATING RNA VIRAL INFECTIONS MODEL MEDICINES, INC. 2023-08-10 US disclosed
WO-2006044856-A2 USE OF A2A ADENOSINE RECEPTOR AGONISTS CV THERAPEUITICS, INC. (US) 2006-04-27 WO disclosed
EP-1492581-A1 POLYMER COATING FOR MEDICAL DEVICES CV THERAPEUTICS, INC. (US) 2005-01-05 EP disclosed
US-20030219562-A1 Polymer coating for medical devices CV THERAPEUTICS, INC. 2003-11-27 US disclosed
WO-2003068289-A1 POLYMER COATING FOR MEDICAL DEVICES CV THERAPEUTICS, INC. (US) 2003-08-21 WO disclosed
US-6403567-B1 N-pyrazole A2A adenosine receptor agonists CV THERAPEUTICS, INC. 2002-06-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12551475-B2 Methods and compositions for treating RNA viral infections SARS1, EIF2AK2, SNRPE ADORA2A 913/4885ADORA3 438/4885ADORA1 762/4885
US-20230301973-A1 TREATMENT OF DIFFUSE INTRINSIC PONTINE GLIOMA ABCC2, SLC2A2, ABCB1 ADORA2A 242/4885ADORA3 903/4885ADORA1 1385/4885
US-20230285556-A1 METHODS AND COMPOSITIONS FOR TREATING CANCER TP53, CD4, MCL1 ADORA2A 1801/4885ADORA3 3648/4885ADORA1 3168/4885
US-20140323712-A1 POLYMORPH OF 2-[4-[(METHYLAMINO)CARBONYL]-1H-PYRAZOL-1-YL]ADENOSINE AMPD2, AMPD1, ADORA2A ADORA2A 3/4885ADORA3 16/4885ADORA1 12/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.