SCHEMBL31490600

SCHEMBL31490600

[Co].c1ccc2nc(-c3ccc4ccccc4n3)ccc2c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 10/20 0.61
NPC1 O15118 9/20 0.61
CYP3A4 P08684 3/20 0.61
CYP1A2 P05177 3/20 0.61
AR P10275 2/20 0.61
CYP2D6 P10635 2/20 0.61
CYP2C9 P11712 1/20 0.61
CYP2C19 P33261 1/20 0.61
MEN1 O00255 3/20 0.59
KMT2A Q03164 3/20 0.59
ALDH1A1 P00352 9/20 0.57
KDM4E B2RXH2 8/20 0.57
HPGD P15428 5/20 0.57
SMN1; SMN2 Q16637 5/20 0.57
HSD17B10 Q99714 4/20 0.57
PKM P14618 4/20 0.57
TP53 P04637 3/20 0.57
MAPT P10636 3/20 0.57
PMP22 Q01453 2/20 0.57
HCRTR1 O43613 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL170196 0.97 RAB9A (0.64) RAB9ANPC1CYP3A4CYP1A2AR
SCHEMBL29374931 0.97 RAB9A (0.64) RAB9ANPC1CYP3A4CYP1A2AR
SCHEMBL28990083 0.94 RAB9A (0.61) RAB9ANPC1CYP3A4CYP1A2AR
SCHEMBL34463709 0.94 RAB9A (0.61) RAB9ANPC1CYP3A4CYP1A2AR
SCHEMBL29607573 0.94 RAB9A (0.63) RAB9ANPC1CYP3A4CYP1A2AR
Hydrochloric Acid SCHEMBL31243061 0.94 ALDH1A1 (0.63) RAB9ANPC1CYP3A4CYP1A2AR
SCHEMBL31365172 0.94 RAB9A (0.61) RAB9ANPC1CYP3A4CYP1A2AR
SCHEMBL30883993 0.94 RAB9A (0.61) RAB9ANPC1CYP3A4CYP1A2AR
SCHEMBL10866984 0.94 RAB9A (0.61) RAB9ANPC1CYP3A4CYP1A2AR
SCHEMBL30103634 0.94 RAB9A (0.61) RAB9ANPC1CYP3A4CYP1A2AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119409630-A Asymmetric polyfluoro-substituted 2,4' -biquinoline-4-amide derivative and preparation method and application thereof 郑州工业应用技术学院 2025-02-11 CN disclosed