SCHEMBL31490972

SCHEMBL31490972

N#CSc1c[nH]c2cccc(Cl)c12

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.49
GPR84 Q9NQS5 1/20 0.49
NR4A2 P43354 1/20 0.41
SLC6A4 P31645 1/20 0.39
GAA P10253 1/20 0.38
DYRK1A Q13627 1/20 0.36
MYC P01106 1/20 0.35
WDR5 P61964 1/20 0.35
PSMB8 P28062 1/20 0.35
RHEB Q15382 1/20 0.34
IMPDH2 P12268 1/20 0.33
IMPDH1 P20839 1/20 0.33
LRRK2 Q5S007 2/20 0.32
ADORA2A P29274 1/20 0.32
ADORA2B P29275 1/20 0.32
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31
ERCC5 P28715 1/20 0.31
FEN1 P39748 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31228753 0.80 GPR84 (0.49) IDO1GPR84IMPDH2IMPDH1LRRK2
SCHEMBL21026823 0.77 IDO1 (0.56) IDO1GPR84NR4A2SLC6A4GAA
SCHEMBL31490960 0.76 HTR2A (0.48) IDO1DYRK1A
SCHEMBL31228906 0.76 CYP2A6 (0.46) GAAIMPDH2IMPDH1
SCHEMBL31490965 0.74 CLK1 (0.41) GAAMYCWDR5
SCHEMBL12309709 0.74 DYRK1A (0.54) IDO1GPR84NR4A2SLC6A4DYRK1A
SCHEMBL4717054 0.73 GPR84 (0.67) IDO1GPR84NR4A2SLC6A4GAA
SCHEMBL15826494 0.72 GPR84 (0.64) IDO1GPR84NR4A2SLC6A4GAA
SCHEMBL29764387 0.72 GPR84 (0.64) IDO1GPR84NR4A2SLC6A4GAA
SCHEMBL11409082 0.72 POLB (0.42) GAAMYCWDR5PSMB8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119823020-A Preparation method of 3-thiocyanatoindole derivative 常州工程职业技术学院 2025-04-15 CN disclosed