Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 3/20 | 0.46 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.40 |
| ▸ | PIM1 | P11309 | 2/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.30 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.30 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23046889 | 0.77 | MEN1 (0.34) | MEN1LMNATHRBKMT2ATDP1 | |
| SCHEMBL31228753 | 0.76 | GPR84 (0.49) | IMPDH2MEN1KMT2AIMPDH1 | |
| SCHEMBL31490972 | 0.76 | IDO1 (0.49) | IMPDH2GAAIMPDH1 | |
| SCHEMBL29952428 | 0.75 | CYP2A6 (0.70) | CYP2A6IMPDH2PIM1PIM3PIM2 | |
| SCHEMBL31490965 | 0.74 | CLK1 (0.41) | MEN1KMT2ATDP1GAA | |
| SCHEMBL31237893 | 0.73 | — | — | |
| SCHEMBL31490960 | 0.73 | HTR2A (0.48) | MEN1KMT2A | |
| SCHEMBL4263872 | 0.71 | LMNA (0.48) | CYP2A6IMPDH2ERN1MEN1LMNA | |
| SCHEMBL7327866 | 0.70 | CYP2A6 (0.54) | CYP2A6IMPDH2PIM1PIM3PIM2 | |
| SCHEMBL15672105 | 0.70 | CYP2A6 (0.54) | CYP2A6IMPDH2PIM1PIM3PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118725317-A | Porphyrin-based cationic covalent organic framework material and preparation method and application thereof | 曲靖师范学院 | 2024-10-01 | — | — | CN | disclosed |