Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31406665 | 1.00 | ESR2 (0.36) | ESR2PKMUSP2SMN1; SMN2NR1H2 | |
| SCHEMBL31670041 | 0.91 | PKM (0.35) | ESR2PKMUSP2SMN1; SMN2NR1H2 | |
| SCHEMBL5251610 | 0.83 | USP2 (0.39) | ESR2USP2SMN1; SMN2NR1H2DDB1 | |
| SCHEMBL31406695 | 0.83 | USP2 (0.39) | ESR2USP2SMN1; SMN2NR1H2DDB1 | |
| SCHEMBL654686 | 0.83 | USP2 (0.39) | ESR2USP2SMN1; SMN2NR1H2DDB1 | |
| SCHEMBL31670015 | 0.82 | PKM (0.35) | ESR2PKMUSP2SMN1; SMN2NR1H2 | |
| SCHEMBL27143468 | 0.82 | EPHX2 (0.39) | ESR2USP2SMN1; SMN2NR1H2DDB1 | |
| SCHEMBL31603730 | 0.81 | RORC (0.37) | ESR2USP2SMN1; SMN2NR1H2HDAC2 | |
| SCHEMBL27143091 | 0.81 | RORC (0.37) | ESR2USP2SMN1; SMN2NR1H2HDAC2 | |
| SCHEMBL27137115 | 0.81 | RORC (0.37) | ESR2USP2SMN1; SMN2NR1H2HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025108443-A2 | HETEROCYCLIC COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | BEIGENE SWITZERLAND GMBH (CH) | 2025-05-30 | — | — | WO | disclosed |
| WO-2025059040-A1 | MUTANT KRAS MODULATORS AND USES THEREOF | NEWAVE PHARMACEUTICAL INC. (US) | 2025-03-20 | — | — | WO | disclosed |
| WO-2025049274-A2 | TETRACYCLIC DERIVATIVES, COMPOSITIONS AND METHODS THEREOF | ENSEM THERAPEUTICS, INC. (US) | 2025-03-06 | — | — | WO | disclosed |