SCHEMBL31491319

SCHEMBL31491319

[O-][S@+]1CCc2nc(-c3ccc(-c4ncco4)cc3)nc(NC3(CO)CCC3)c21

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ LATS1 O95835 6/20 0.41
▸ LATS2 Q9NRM7 3/20 0.41
▸ TRPV3 Q8NET8 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31491290 0.96 LATS1 (0.36) LATS1LATS2
SCHEMBL31491285 0.89 LATS1 (0.30) LATS1LATS2
SCHEMBL31491335 0.85 — —
SCHEMBL31491386 0.85 — —
SCHEMBL31083959 0.84 LATS1 (0.43) LATS1LATS2TRPV3
SCHEMBL31083989 0.83 LATS1 (0.41) LATS1LATS2
SCHEMBL31491323 0.83 LATS1 (0.38) LATS1LATS2
SCHEMBL31491363 0.83 LATS1 (0.38) LATS1LATS2
SCHEMBL31084098 0.82 LATS1 (0.42) LATS1LATS2
SCHEMBL31083981 0.81 TRPV3 (0.44) LATS1LATS2TRPV3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025067168-A1 AZA FUSED RING COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF 苏州爱科百发生物医药技术有限公司 2025-04-03 — — WO disclosed
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