SCHEMBL31491323

SCHEMBL31491323

Cc1noc(-c2ccc(-c3nc4c(c(NC5(CO)CCC5)n3)[S@+]([O-])CC4)cc2)n1

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ LATS1 O95835 5/20 0.38
▸ LATS2 Q9NRM7 3/20 0.38
▸ LMNA P02545 1/20 0.33
▸ THRB P10828 1/20 0.33
▸ ACHE P22303 1/20 0.33
▸ TP53 P04637 1/20 0.32
▸ MAPT P10636 1/20 0.32
▸ PIK3CD O00329 1/20 0.31
▸ PIK3CB P42338 1/20 0.31
▸ PIK3CG P48736 1/20 0.31
▸ OPRK1 P41145 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31491363 0.86 LATS1 (0.38) LATS1LATS2
SCHEMBL31083959 0.83 LATS1 (0.43) LATS1LATS2
SCHEMBL31491319 0.83 LATS1 (0.41) LATS1LATS2
SCHEMBL31083963 0.82 LATS1 (0.41) LATS1LATS2LMNATP53MAPT
SCHEMBL31084020 0.81 LATS1 (0.40) LATS1LATS2
SCHEMBL31084006 0.81 LATS1 (0.40) LATS1LATS2
SCHEMBL31083981 0.81 TRPV3 (0.44) LATS1LATS2
SCHEMBL31083989 0.81 LATS1 (0.41) LATS1LATS2
SCHEMBL31084044 0.80 LATS1 (0.39) LATS1LATS2LMNAMAPT
SCHEMBL31084098 0.80 LATS1 (0.42) LATS1LATS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025067168-A1 AZA FUSED RING COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF 苏州爱科百发生物医药技术有限公司 2025-04-03 — — WO disclosed
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