Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.31 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.31 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31491368 | 0.78 | KCNJ1 (0.32) | — | |
| SCHEMBL31491313 | 0.78 | NPC1 (0.35) | APPGPR84IP6K1TTBK1TTBK2 | |
| SCHEMBL22734117 | 0.72 | KMT2A (0.34) | — | |
| SCHEMBL22734119 | 0.70 | TLR8 (0.37) | — | |
| SCHEMBL31491395 | 0.70 | CD274 (0.34) | — | |
| SCHEMBL22734113 | 0.70 | LMNA (0.37) | — | |
| SCHEMBL31491366 | 0.67 | KIF11 (0.39) | — | |
| SCHEMBL30785590 | 0.67 | EZH2 (0.37) | — | |
| SCHEMBL22734112 | 0.67 | ESR1 (0.40) | — | |
| SCHEMBL30785579 | 0.64 | KDM4E (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025067168-A1 | AZA FUSED RING COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 苏州爱科百发生物医药技术有限公司 | 2025-04-03 | — | — | WO | disclosed |