Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 3/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.35 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.35 |
| ▸ | ACP1 | P24666 | 1/20 | 0.33 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.33 |
| ▸ | SGK1 | O00141 | 3/20 | 0.32 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.31 |
| ▸ | LATS1 | O95835 | 1/20 | 0.31 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.31 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.30 |
| ▸ | AXL | P30530 | 1/20 | 0.30 |
| ▸ | MERTK | Q12866 | 1/20 | 0.30 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.30 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31491271 | 0.85 | ADORA1 (0.39) | ADORA1ADORA2AADORA3ADORA2BACP1 | |
| SCHEMBL31491291 | 0.82 | ADORA2A (0.37) | ADORA1ADORA2AADORA3ADORA2BMAPK14 | |
| SCHEMBL31491363 | 0.76 | LATS1 (0.38) | MAPK14MAPK11LATS1LATS2 | |
| SCHEMBL31491311 | 0.74 | LTA4H (0.33) | — | |
| SCHEMBL31491337 | 0.72 | PRKCI (0.34) | MAPK14IRAK1 | |
| SCHEMBL31491283 | 0.71 | GSK3B (0.37) | MAPK14 | |
| SCHEMBL31491327 | 0.71 | GSK3B (0.37) | MAPK14 | |
| SCHEMBL31474619 | 0.71 | ADORA3 (0.32) | ADORA1ADORA2AADORA3ADORA2B | |
| SCHEMBL31474601 | 0.70 | S1PR5 (0.32) | MAPK14AXLMERTK | |
| SCHEMBL12921298 | 0.69 | MAPT (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025067168-A1 | AZA FUSED RING COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 苏州爱科百发生物医药技术有限公司 | 2025-04-03 | — | — | WO | disclosed |