Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 2/20 | 0.40 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.40 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31492111 | 0.88 | KDR (0.50) | MAOAMAOBMAPTALDH1A1KDM4E | |
| SCHEMBL31492114 | 0.87 | MEN1 (0.45) | MAPTALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL31491991 | 0.87 | KDR (0.44) | MAPTALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL31492026 | 0.84 | ALDH1A1 (0.47) | MAOBMAPTALDH1A1KDM4ETDP1 | |
| SCHEMBL14075826 | 0.83 | MAPT (0.56) | MAPTALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL470031 | 0.83 | MAPT (0.56) | MAPTALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL469859 | 0.81 | CA1 (0.50) | MAOAMAOBMAPTALDH1A1KDM4E | |
| SCHEMBL31492003 | 0.81 | MAPT (0.50) | MAPTALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL31492056 | 0.81 | MAPT (0.53) | MAPTALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL31492027 | 0.81 | MAPT (0.46) | MAPTALDH1A1KDM4ETDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025046420-A1 | COMPOUND TARGETING EGR-1 AND USE THEREOF FOR TREATMENT OF ATOPIC DERMATITIS | 주식회사 아제라메디 | 2025-03-06 | — | — | WO | claimed |
| WO-2025046420-A1 | COMPOUND TARGETING EGR-1 AND USE THEREOF FOR TREATMENT OF ATOPIC DERMATITIS | 주식회사 아제라메디 | 2025-03-06 | — | — | WO | disclosed |