Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL470016 | 0.89 | KDR (0.53) | MAPTALDH1A1NPC1SMN1; SMN2RAB9A | |
| SCHEMBL31492111 | 0.89 | KDR (0.50) | MAPTALDH1A1SMN1; SMN2KMT2ALMNA | |
| SCHEMBL31492055 | 0.85 | LRRK2 (0.52) | MAPTALDH1A1NPC1SMN1; SMN2RAB9A | |
| SCHEMBL31492086 | 0.83 | ALDH1A1 (0.51) | MAPTALDH1A1NPC1SMN1; SMN2RAB9A | |
| SCHEMBL469859 | 0.83 | CA1 (0.50) | MAPTALDH1A1KDM4EIDO1AGTR1 | |
| SCHEMBL31492083 | 0.82 | ALDH1A1 (0.54) | MAPTALDH1A1NPC1SMN1; SMN2RAB9A | |
| SCHEMBL469845 | 0.81 | AGTR1 (0.57) | MAPTALDH1A1KMT2ALMNAGAA | |
| SCHEMBL469862 | 0.81 | KDR (0.48) | MAPTALDH1A1NPC1SMN1; SMN2RAB9A | |
| SCHEMBL18955763 | 0.81 | CA1 (0.55) | MAPTALDH1A1NPC1SMN1; SMN2RAB9A | |
| SCHEMBL31492017 | 0.81 | MAOA (0.50) | MAPTALDH1A1NPC1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025046420-A1 | COMPOUND TARGETING EGR-1 AND USE THEREOF FOR TREATMENT OF ATOPIC DERMATITIS | 주식회사 아제라메디 | 2025-03-06 | — | — | WO | disclosed |