Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.62 |
| ▸ | HTT | P42858 | 4/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.62 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | SPAST | Q9UBP0 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30704217 | 0.83 | LATS1 (0.49) | LMNAHTTSMN1; SMN2NCOA3ALDH1A1 | |
| SCHEMBL31540829 | 0.83 | LATS1 (0.49) | LMNAHTTSMN1; SMN2NCOA3ALDH1A1 | |
| SCHEMBL31745311 | 0.82 | HTT (0.63) | LMNAHTTSMN1; SMN2NCOA3ALDH1A1 | |
| SCHEMBL31259000 | 0.82 | HTR2C (0.46) | LMNAHTTSMN1; SMN2NCOA3SPAST | |
| SCHEMBL29813234 | 0.82 | HTR2A (0.46) | LMNAHTTSMN1; SMN2NCOA3SPAST | |
| SCHEMBL11882183 | 0.82 | LMNA (0.47) | LMNAHTTSMN1; SMN2NCOA3HRH4 | |
| SCHEMBL27911852 | 0.79 | HTT (0.47) | LMNAHTTSMN1; SMN2NCOA3HRH4 | |
| SCHEMBL14094443 | 0.78 | HTR2C (0.59) | HRH4TSHRSPASTCYP3A4CYP2C19 | |
| SCHEMBL1205270 | 0.78 | HTR2C (0.59) | HRH4TSHRSPASTCYP3A4CYP2C19 | |
| SCHEMBL5667529 | 0.77 | SPAST (0.43) | LMNAHTTSMN1; SMN2NCOA3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119677726-A | KRAS inhibitors | 百时美施贵宝公司 | 2025-03-21 | — | — | CN | disclosed |