Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN7 | P35236 | 15/20 | 1.00 |
| ▸ | HSPA1A | P0DMV8 | 13/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 1.00 |
| ▸ | GAPDH | P04406 | 8/20 | 0.71 |
| ▸ | POLB | P06746 | 5/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.71 |
| ▸ | MEN1 | O00255 | 4/20 | 0.71 |
| ▸ | BLM | P54132 | 4/20 | 0.71 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.71 |
| ▸ | MIF | P14174 | 1/20 | 0.71 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.67 |
| ▸ | CDC25B | P30305 | 3/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | RECQL | P46063 | 3/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | MASP2 | O00187 | 3/20 | 0.67 |
| ▸ | CD44 | P16070 | 3/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26098723 | 1.00 | PTPN7 (1.00) | PTPN7HSPA1ATDP1GAPDHPOLB | |
| SCHEMBL16706087 | 0.83 | PTPN7 (1.00) | PTPN7HSPA1ATDP1GAPDHPOLB | |
| SCHEMBL29415450 | 0.81 | PTPN7 (1.00) | PTPN7HSPA1ATDP1GAPDHPOLB | |
| SCHEMBL3610631 | 0.81 | CDC25B (1.00) | PTPN7HSPA1ATDP1GAPDHPOLB | |
| SCHEMBL2116528 | 0.81 | PTPN7 (1.00) | PTPN7HSPA1ATDP1GAPDHPOLB | |
| SCHEMBL2808722 | 0.81 | PTPN7 (1.00) | PTPN7HSPA1ATDP1GAPDHPOLB | |
| SCHEMBL13186581 | 0.81 | PTPN7 (0.73) | PTPN7HSPA1ATDP1GAPDHPOLB | |
| SCHEMBL6678349 | 0.79 | PTPN7 (0.65) | PTPN7HSPA1ATDP1GAPDHPOLB | |
| SCHEMBL2116061 | 0.79 | PTPN7 (1.00) | PTPN7HSPA1ATDP1GAPDHPOLB | |
| SCHEMBL29954899 | 0.79 | POLB (1.00) | PTPN7HSPA1ATDP1GAPDHPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250090566-A1 | BACTERIAL DNA GYRASE INHIBITORS AND METHODS OF USE THEREOF | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) | 2025-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250090566-A1 | BACTERIAL DNA GYRASE INHIBITORS AND METHODS OF USE THEREOF | TOP1, DNA2, TOP2A | PTPN7 4543/4885HSPA1A 1352/4885TDP1 63/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.