Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 8/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 8/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 1.00 |
| ▸ | GAA | P10253 | 4/20 | 1.00 |
| ▸ | MASP2 | O00187 | 3/20 | 1.00 |
| ▸ | MCL1 | Q07820 | 2/20 | 1.00 |
| ▸ | USP2 | O75604 | 2/20 | 1.00 |
| ▸ | NSD2 | O96028 | 1/20 | 1.00 |
| ▸ | ALPL | P05186 | 1/20 | 1.00 |
| ▸ | APOBEC3A | P31941 | 1/20 | 1.00 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 1.00 |
| ▸ | PTPN7 | P35236 | 14/20 | 0.81 |
| ▸ | HSPA1A | P0DMV8 | 13/20 | 0.81 |
| ▸ | CDC25B | P30305 | 2/20 | 0.81 |
| ▸ | CD44 | P16070 | 2/20 | 0.81 |
| ▸ | MSN | P26038 | 2/20 | 0.81 |
| ▸ | EZH2 | Q15910 | 2/20 | 0.81 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.81 |
| ▸ | AKT1 | P31749 | 1/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16706084 | 1.00 | POLB (1.00) | POLBKMT2AALDH1A1L3MBTL1GAA | |
| SCHEMBL29415450 | 0.90 | PTPN7 (1.00) | POLBKMT2AALDH1A1L3MBTL1GAA | |
| SCHEMBL2808722 | 0.90 | PTPN7 (1.00) | POLBKMT2AALDH1A1L3MBTL1GAA | |
| SCHEMBL17211738 | 0.85 | HSPA1A (0.81) | POLBKMT2AALDH1A1L3MBTL1GAA | |
| SCHEMBL2116528 | 0.85 | PTPN7 (1.00) | POLBKMT2AALDH1A1L3MBTL1GAA | |
| SCHEMBL13725129 | 0.84 | PTPN7 (1.00) | POLBKMT2AALDH1A1L3MBTL1GAA | |
| SCHEMBL13856706 | 0.84 | PTPN7 (1.00) | POLBKMT2AALDH1A1L3MBTL1GAA | |
| SCHEMBL1066515 | 0.84 | PTPN7 (1.00) | POLBKMT2AALDH1A1L3MBTL1GAA | |
| SCHEMBL15033517 | 0.84 | POLB (1.00) | POLBKMT2AALDH1A1L3MBTL1GAA | |
| SCHEMBL13186581 | 0.82 | PTPN7 (0.73) | POLBKMT2AALDH1A1L3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |