Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 3/20 | 0.41 |
| ▸ | CLK1 | P49759 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26260595 | 0.86 | DYRK1A (0.43) | CLK1DYRK1AFYNKDM4EALDH1A1 | |
| SCHEMBL26260522 | 0.85 | MAPT (0.36) | KDM4EALDH1A1LMNASMN1; SMN2HTT | |
| SCHEMBL30041441 | 0.85 | MAPT (0.36) | KDM4EALDH1A1LMNASMN1; SMN2HTT | |
| SCHEMBL25401802 | 0.83 | MEN1 (0.46) | ALDH1A1MAPTMEN1KMT2AABCG2 | |
| SCHEMBL30040331 | 0.77 | MAPT (0.39) | ALDH1A1LMNASMN1; SMN2NPSR1PTGS2 | |
| SCHEMBL21611940 | 0.77 | MAPT (0.39) | ALDH1A1LMNASMN1; SMN2NPSR1PTGS2 | |
| SCHEMBL26260574 | 0.77 | FABP4 (0.36) | KDM4EALDH1A1LMNASMN1; SMN2LCK | |
| SCHEMBL21611930 | 0.76 | CYP2C9 (0.42) | KDM4EALDH1A1LMNASMN1; SMN2HTT | |
| SCHEMBL21611920 | 0.76 | CYP2C19 (0.54) | SMN1; SMN2MAPTTP53ADORA2ATDP1 | |
| SCHEMBL21612050 | 0.75 | TP53 (0.39) | KDM4EALDH1A1LMNASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4085054-B1 | NEW PQSR INVERSE AGONISTS | HELMHOLTZ ZENTRUM INFEKTIONSFORSCHUNG GMBH (DE) | 2025-02-19 | — | — | EP | disclosed |