Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | REN | P00797 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.35 |
| ▸ | GHSR | Q92847 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | USP1 | O94782 | 2/20 | 0.34 |
| ▸ | WDR48 | Q8TAF3 | 2/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26260522 | 1.00 | MAPT (0.36) | MAPTADORA2ATP53TDP1SMN1; SMN2 | |
| SCHEMBL26260596 | 0.86 | REN (0.38) | SMN1; SMN2RENGHSR | |
| SCHEMBL31493183 | 0.85 | SYK (0.41) | MAPTADORA2ATP53TDP1SMN1; SMN2 | |
| SCHEMBL30040331 | 0.83 | MAPT (0.39) | MAPTTDP1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL21611940 | 0.83 | MAPT (0.39) | MAPTTDP1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL21611920 | 0.80 | CYP2C19 (0.54) | MAPTADORA2ATP53TDP1SMN1; SMN2 | |
| SCHEMBL21611930 | 0.78 | CYP2C9 (0.42) | MAPTADORA2ATP53TDP1SMN1; SMN2 | |
| SCHEMBL25401802 | 0.77 | MEN1 (0.46) | MAPTALDH1A1 | |
| SCHEMBL26260574 | 0.77 | FABP4 (0.36) | MAPTADORA2ATP53TDP1SMN1; SMN2 | |
| SCHEMBL26261427 | 0.76 | USP1 (0.34) | MAPTADORA2ATP53TDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4085054-B1 | NEW PQSR INVERSE AGONISTS | HELMHOLTZ ZENTRUM INFEKTIONSFORSCHUNG GMBH (DE) | 2025-02-19 | — | — | EP | disclosed |
| EP-4085054-A1 | NEW PQSR INVERSE AGONISTS | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2022-11-09 | — | — | EP | disclosed |