Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27218823 | 1.00 | HSD17B10 (0.44) | HSD17B10POLBHPGDALDH1A1MAPT | |
| SCHEMBL27218896 | 0.89 | SMN1; SMN2 (0.48) | HSD17B10POLBHPGDALDH1A1MAPT | |
| SCHEMBL27218662 | 0.88 | POLB (0.42) | POLBHPGDALDH1A1MAPTLMNA | |
| SCHEMBL27218675 | 0.86 | SMN1; SMN2 (0.50) | HSD17B10POLBHPGDALDH1A1MAPT | |
| SCHEMBL31494314 | 0.84 | HPGD (0.47) | HSD17B10POLBHPGDALDH1A1MAPT | |
| SCHEMBL27218919 | 0.84 | HPGD (0.47) | HSD17B10POLBHPGDALDH1A1MAPT | |
| SCHEMBL27218752 | 0.83 | LMNA (0.50) | HSD17B10POLBHPGDALDH1A1MAPT | |
| SCHEMBL27218826 | 0.83 | ALDH1A1 (0.39) | HSD17B10POLBHPGDALDH1A1MAPT | |
| SCHEMBL31494300 | 0.83 | ALDH1A1 (0.39) | HSD17B10POLBHPGDALDH1A1MAPT | |
| SCHEMBL27218651 | 0.82 | SMN1; SMN2 (0.44) | HSD17B10POLBHPGDALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4232448-B1 | AGONISTS OF FREE FATTY ACID RECEPTOR 1 AND THEIR USE IN DISEASES ASSOCIATED WITH SAID RECEPTOR | Halo Therapeutics Ltd (GB) | 2025-05-07 | — | — | EP | claimed |
| EP-3956323-B1 | OXAZOLE AND OXADIAZOLE DERIVATIVES USEFUL AS AGONISTS OF FREE FATTY ACID RECEPTOR 1 | Halo Therapeutics Ltd (GB) | 2025-03-05 | — | — | EP | claimed |