Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31494452 | 0.87 | MAPK1 (0.45) | MAPTSMN1; SMN2GAAALDH1A1TSHR | |
| SCHEMBL31494422 | 0.87 | RAB9A (0.55) | MAPTSMN1; SMN2GAAALDH1A1HPGD | |
| SCHEMBL31494432 | 0.85 | GAA (0.53) | MAPTSMN1; SMN2GAAALDH1A1HPGD | |
| SCHEMBL31494404 | 0.84 | MAPT (0.44) | MAPTSMN1; SMN2GAAALDH1A1TSHR | |
| SCHEMBL31494362 | 0.83 | GAA (0.51) | MAPTSMN1; SMN2GAAALDH1A1HPGD | |
| SCHEMBL27218792 | 0.83 | CA12 (0.48) | MAPTSMN1; SMN2GAAALDH1A1TSHR | |
| SCHEMBL27218901 | 0.82 | RAB9A (0.44) | MAPTSMN1; SMN2GAAALDH1A1TSHR | |
| SCHEMBL31494420 | 0.81 | GAA (0.48) | MAPTSMN1; SMN2GAAALDH1A1HPGD | |
| SCHEMBL27218916 | 0.81 | MAPT (0.50) | MAPTSMN1; SMN2GAAALDH1A1HPGD | |
| SCHEMBL31494458 | 0.80 | RAB9A (0.54) | MAPTSMN1; SMN2GAAALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4232448-B1 | AGONISTS OF FREE FATTY ACID RECEPTOR 1 AND THEIR USE IN DISEASES ASSOCIATED WITH SAID RECEPTOR | Halo Therapeutics Ltd (GB) | 2025-05-07 | — | — | EP | disclosed |
| EP-3956323-B1 | OXAZOLE AND OXADIAZOLE DERIVATIVES USEFUL AS AGONISTS OF FREE FATTY ACID RECEPTOR 1 | Halo Therapeutics Ltd (GB) | 2025-03-05 | — | — | EP | disclosed |