Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31494392 | 0.86 | CLK1 (0.46) | MAPTCHRM2CHRM5CHRM1NPC1 | |
| SCHEMBL31494452 | 0.84 | MAPK1 (0.45) | MAPTCHRM2CHRM5CHRM1NPC1 | |
| SCHEMBL31494388 | 0.84 | MAPT (0.54) | MAPTNPC1RAB9AMAPK1L3MBTL1 | |
| SCHEMBL31494450 | 0.82 | MAPT (0.47) | MAPTCHRM2CHRM5CHRM1NPC1 | |
| SCHEMBL31494445 | 0.82 | CHRM2 (0.44) | MAPTCHRM2CHRM5CHRM1NPC1 | |
| SCHEMBL27218792 | 0.80 | CA12 (0.48) | MAPTCHRM2CHRM5CHRM1NPC1 | |
| SCHEMBL27218901 | 0.78 | RAB9A (0.44) | MAPTNPC1RAB9AMAPK1TSHR | |
| SCHEMBL31494431 | 0.78 | RAB9A (0.45) | MAPTCHRM2CHRM5CHRM1NPC1 | |
| SCHEMBL31494432 | 0.76 | GAA (0.53) | MAPTNPC1RAB9AMAPK1L3MBTL1 | |
| SCHEMBL27218716 | 0.76 | SMN1; SMN2 (0.56) | MAPTCHRM2CHRM5CHRM1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4232448-B1 | AGONISTS OF FREE FATTY ACID RECEPTOR 1 AND THEIR USE IN DISEASES ASSOCIATED WITH SAID RECEPTOR | Halo Therapeutics Ltd (GB) | 2025-05-07 | — | — | EP | disclosed |
| EP-3956323-B1 | OXAZOLE AND OXADIAZOLE DERIVATIVES USEFUL AS AGONISTS OF FREE FATTY ACID RECEPTOR 1 | Halo Therapeutics Ltd (GB) | 2025-03-05 | — | — | EP | disclosed |