Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.64 |
| ▸ | NPC1 | O15118 | 5/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.64 |
| ▸ | LMNA | P02545 | 4/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31494430 | 0.85 | SMN1; SMN2 (0.72) | RAB9ANPC1SMN1; SMN2LMNAHTT | |
| SCHEMBL27218886 | 0.84 | SMN1; SMN2 (0.70) | RAB9ANPC1SMN1; SMN2LMNAHTT | |
| SCHEMBL29808248 | 0.82 | NPC1 (0.46) | RAB9ANPC1SMN1; SMN2LMNAHTT | |
| SCHEMBL27218936 | 0.82 | RAB9A (0.71) | RAB9ANPC1SMN1; SMN2LMNAHTT | |
| SCHEMBL27218874 | 0.81 | HTT (0.69) | RAB9ANPC1SMN1; SMN2LMNAHTT | |
| SCHEMBL27218688 | 0.80 | ALDH1A1 (0.62) | RAB9ANPC1SMN1; SMN2LMNAHTT | |
| SCHEMBL27218761 | 0.79 | RAB9A (0.64) | RAB9ANPC1SMN1; SMN2LMNAHTT | |
| SCHEMBL27218899 | 0.77 | SMN1; SMN2 (0.58) | RAB9ANPC1SMN1; SMN2LMNAHTT | |
| SCHEMBL27218810 | 0.76 | NPC1 (0.61) | RAB9ANPC1SMN1; SMN2LMNAHTT | |
| SCHEMBL27218689 | 0.75 | HTT (0.55) | RAB9ANPC1SMN1; SMN2LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4232448-B1 | AGONISTS OF FREE FATTY ACID RECEPTOR 1 AND THEIR USE IN DISEASES ASSOCIATED WITH SAID RECEPTOR | Halo Therapeutics Ltd (GB) | 2025-05-07 | — | — | EP | disclosed |
| EP-3956323-B1 | OXAZOLE AND OXADIAZOLE DERIVATIVES USEFUL AS AGONISTS OF FREE FATTY ACID RECEPTOR 1 | Halo Therapeutics Ltd (GB) | 2025-03-05 | — | — | EP | disclosed |