Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27218673 | 0.86 | RAB9A (0.46) | RAB9ANPC1SMN1; SMN2HTTLMNA | |
| SCHEMBL27218748 | 0.85 | RAB9A (0.50) | RAB9ANPC1SMN1; SMN2HTTLMNA | |
| SCHEMBL31528335 | 0.85 | RAB9A (0.50) | RAB9ANPC1SMN1; SMN2HTTLMNA | |
| SCHEMBL27218782 | 0.82 | RAB9A (0.47) | RAB9ANPC1SMN1; SMN2HTTLMNA | |
| SCHEMBL27218708 | 0.79 | RAB9A (0.49) | RAB9ANPC1SMN1; SMN2HTTLMNA | |
| SCHEMBL27218817 | 0.78 | RAB9A (0.50) | RAB9ANPC1SMN1; SMN2HTTLMNA | |
| SCHEMBL31494410 | 0.72 | RAB9A (0.52) | RAB9ANPC1SMN1; SMN2HTTLMNA | |
| SCHEMBL27218777 | 0.71 | RAB9A (0.48) | RAB9ANPC1SMN1; SMN2HTTLMNA | |
| SCHEMBL27218874 | 0.71 | HTT (0.69) | RAB9ANPC1SMN1; SMN2HTTLMNA | |
| SCHEMBL14214596 | 0.71 | PKM (0.39) | RAB9ANPC1SMN1; SMN2HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4232448-B1 | AGONISTS OF FREE FATTY ACID RECEPTOR 1 AND THEIR USE IN DISEASES ASSOCIATED WITH SAID RECEPTOR | Halo Therapeutics Ltd (GB) | 2025-05-07 | — | — | EP | disclosed |
| EP-3956323-B1 | OXAZOLE AND OXADIAZOLE DERIVATIVES USEFUL AS AGONISTS OF FREE FATTY ACID RECEPTOR 1 | Halo Therapeutics Ltd (GB) | 2025-03-05 | — | — | EP | disclosed |