Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HCAR1 | Q9BXC0 | 2/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.34 |
| ▸ | CDK2 | P24941 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31494904 | 0.90 | CCNE2 (0.38) | MAT2ACCNE2CCNE1CDK2CYP3A4 | |
| SCHEMBL31494966 | 0.89 | MAT2A (0.39) | MAT2ATP53HCAR1JAK2BTK | |
| SCHEMBL31494872 | 0.89 | TP53 (0.46) | MAT2ATP53HCAR1KDM4EHTT | |
| SCHEMBL31494853 | 0.85 | JAK2 (0.36) | TP53HCAR1PDE2APDE10AJAK2 | |
| SCHEMBL31494843 | 0.85 | MAT2A (0.38) | MAT2AHCAR1PDE2APDE10ACYP3A4 | |
| SCHEMBL31494810 | 0.85 | PDE7A (0.35) | PDE2APDE10ACCNE2CCNE1CDK2 | |
| SCHEMBL31494834 | 0.84 | GABRA1 (0.35) | HCAR1JAK2BTKCCNE2CCNE1 | |
| SCHEMBL31494808 | 0.84 | MAT2A (0.40) | MAT2ATP53KDM4ERXFP1GRIN1 | |
| SCHEMBL31494923 | 0.83 | KDM4E (0.35) | TP53HCAR1JAK2BTKKDM4E | |
| SCHEMBL31494841 | 0.83 | MAT2A (0.53) | MAT2APDE2APDE10ARXFP1GRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025037871-A1 | TRICYCLIC COMPOUND AND USE THEREOF AS MAT2A INHIBITOR | 에스케이바이오팜 주식회사 | 2025-02-20 | — | — | WO | claimed |
| WO-2025037871-A1 | TRICYCLIC COMPOUND AND USE THEREOF AS MAT2A INHIBITOR | 에스케이바이오팜 주식회사 | 2025-02-20 | — | — | WO | disclosed |