Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP1 | O94782 | 14/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31496659 | 0.85 | USP1 (0.52) | USP1 | |
| SCHEMBL31155941 | 0.79 | USP1 (0.44) | USP1PTGS2PTGS1 | |
| SCHEMBL29043900 | 0.79 | USP1 (0.42) | USP1PTGS2PTGS1 | |
| SCHEMBL31155901 | 0.79 | USP1 (0.45) | USP1PTGS2PTGS1 | |
| SCHEMBL30462024 | 0.79 | USP1 (0.42) | USP1PTGS2PTGS1 | |
| SCHEMBL31496713 | 0.79 | USP1 (0.45) | USP1 | |
| SCHEMBL31255086 | 0.78 | USP1 (0.42) | USP1PTGS2PTGS1 | |
| SCHEMBL25978632 | 0.77 | USP1 (0.44) | USP1PTGS2PTGS1 | |
| SCHEMBL31496670 | 0.76 | USP1 (0.44) | USP1 | |
| SCHEMBL26627762 | 0.75 | USP1 (0.48) | USP1PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250145590-A1 | UBIQUITIN SPECIFIC PROCESSING PROTEASE 1 (USP1) COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250145590-A1 | UBIQUITIN SPECIFIC PROCESSING PROTEASE 1 (USP1) COMPOUNDS | USP1, UBA1, SUMO1 | USP1 1/4885PTGS2 2550/4885PTGS1 641/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.