Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUSP3 | P51452 | 1/20 | 0.61 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.61 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.61 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.61 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.51 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28853970 | 0.85 | FOLH1 (0.49) | DUSP3PTPN5PTPN11CTDSP1FOLH1 | |
| SCHEMBL22912 | 0.83 | FOLH1 (0.59) | FOLH1HMGB1ALDH1A1ALOX15CLCN2 | |
| SCHEMBL31090800 | 0.83 | FOLH1 (0.50) | DUSP3PTPN5PTPN11CTDSP1FOLH1 | |
| SCHEMBL23708 | 0.83 | FOLH1 (0.50) | DUSP3PTPN5PTPN11CTDSP1FOLH1 | |
| SCHEMBL29367715 | 0.83 | FOLH1 (0.50) | DUSP3PTPN5PTPN11CTDSP1FOLH1 | |
| Acetic Acid SCHEMBL6336451 | 0.83 | FOLH1 (0.47) | DUSP3PTPN5PTPN11CTDSP1FOLH1 | |
| SCHEMBL29140649 | 0.83 | FOLH1 (0.47) | DUSP3PTPN5PTPN11CTDSP1FOLH1 | |
| SCHEMBL605775 | 0.82 | FOLH1 (0.49) | DUSP3PTPN5PTPN11CTDSP1FOLH1 | |
| SCHEMBL5553275 | 0.82 | FOLH1 (0.49) | DUSP3PTPN5PTPN11CTDSP1FOLH1 | |
| SCHEMBL8482542 | 0.82 | FOLH1 (0.49) | DUSP3PTPN5PTPN11CTDSP1FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1976801-A2 | MODIFIED NANOSTRUCTURED TITANIA MATERIALS AND METHODS OF MANUFACTURE | National Center for Scientific Research Demokritos (GR) | 2008-10-08 | — | — | EP | claimed |
| WO-2007085911-A2 | MODIFIED NANOSTRUCTURED TITANIA MATERIALS AND METHODS OF MANUFACTURE | NATIONAL CENTER FOR SCIENTIFIC RESEARCH DEMOKRITOS (GR) | 2007-08-02 | — | — | WO | claimed |
| EP-0399755-A1 | Light-sensitive composition and presensitized plate for use in making lithographic printing plates | Fuji Photo Film Co., Ltd. (JP) | 1990-11-28 | — | — | EP | claimed |
| US-8404434-B2 | Method for determining degree of negative effect of macrophages on vertebrate | YAMASA CORPORATION (JP) | 2013-03-26 | — | — | US | disclosed |
| US-20100151585-A1 | Method for determining degree of negative effect of macrophages on vertebrate | HAMAOKI MASARU | 2010-06-17 | — | — | US | disclosed |
| US-7687231-B2 | Method for determining degree of negative effect of macrophages on vertebrate | YAMASA CORPORATION (JP) | 2010-03-30 | — | — | US | disclosed |
| EP-1745143-A4 | METHODS AND TOOLS FOR DETECTING COLLAGEN DEGRADATION | CAMBREX BIO SCIENCE WALKERSVIL (US) | 2009-07-29 | — | — | EP | disclosed |
| US-20080299604-A1 | METHODS AND TOOLS FOR DETECTING COLLAGEN DEGRADATION | LONZA WALKERSVILLE, INC. (US) | 2008-12-04 | — | — | US | disclosed |
| US-7405037-B2 | Methods and tools for detecting collagen degradation | LONZA WALKERSVILLE, INC. (US) | 2008-07-29 | — | — | US | disclosed |
| US-20070202554-A1 | Method for determining degree of negative effect of macrophages on vertebrate | YAMASA CORPORATION (JP) | 2007-08-30 | — | — | US | disclosed |
| EP-1745143-A1 | METHODS AND TOOLS FOR DETECTING COLLAGEN DEGRADATION | Cambrex Bio Science Walkersville, Inc (US) | 2007-01-24 | — | — | EP | disclosed |
| WO-2005113794-A1 | METHODS AND TOOLS FOR DETECTING COLLAGEN DEGRADATION | CAMBREX BIO SCIENCE WALKERSVILLE, INC. (US) | 2005-12-01 | — | — | WO | disclosed |
| US-20050250171-A1 | Methods and tools for detecting collagen degradation | CAMBREX BIO SCIENCE WALKERSVILLE, INC. (US) | 2005-11-10 | — | — | US | disclosed |
| US-20010055776-A1 | High throughput cell-based assay kits | GREENWALT DALE (US) | 2001-12-27 | — | — | US | disclosed |
| EP-0399755-A1 | Light-sensitive composition and presensitized plate for use in making lithographic printing plates | Fuji Photo Film Co., Ltd. (JP) | 1990-11-28 | — | — | EP | disclosed |