Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC42 | P60953 | 1/20 | 0.53 |
| ▸ | RB1 | P06400 | 7/20 | 0.51 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.47 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4192405 | 0.89 | RB1 (0.60) | CDC42RB1SIRT1SIRT2GAA | |
| Hydrochloric Acid SCHEMBL4157308 | 0.88 | RB1 (0.60) | CDC42RB1SIRT1SIRT2GAA | |
| SCHEMBL31497396 | 0.87 | CDC42 (0.57) | CDC42RB1SIRT1SIRT2GAA | |
| SCHEMBL31497427 | 0.87 | RB1 (0.55) | CDC42RB1SIRT1SIRT2GAA | |
| SCHEMBL31497389 | 0.87 | SIRT1 (0.53) | CDC42RB1SIRT1SIRT2GAA | |
| SCHEMBL31497468 | 0.82 | RB1 (0.52) | CDC42RB1SIRT1SIRT2GAA | |
| SCHEMBL31497401 | 0.82 | RB1 (0.52) | CDC42RB1SIRT1SIRT2GAA | |
| SCHEMBL31497455 | 0.82 | RB1 (0.52) | CDC42RB1SIRT1SIRT2GAA | |
| SCHEMBL5445892 | 0.80 | CDC42 (0.60) | CDC42GAACASP6BRD3PRMT5 | |
| SCHEMBL5454077 | 0.79 | CDC42 (0.58) | CDC42SIRT1SIRT2GAACASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119490487-A | Polysubstituted tetrahydrocarbazole compound, preparation method, pharmaceutical composition and application thereof | 中国科学院上海药物研究所 | 2025-02-21 | — | — | CN | disclosed |